Immunohistochemical overexpression of p16 and p53 in uterine serous carcinoma and ovarian high-grade serous carcinoma.

@article{ChiesaVottero2007ImmunohistochemicalOO,
  title={Immunohistochemical overexpression of p16 and p53 in uterine serous carcinoma and ovarian high-grade serous carcinoma.},
  author={Andres G Chiesa-Vottero and Anais Malpica and Michael T. Deavers and Russell E. Broaddus and Gerard J Nuovo and Elvio Gilberto da Silva},
  journal={International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists},
  year={2007},
  volume={26 3},
  pages={328-33}
}
The immunohistochemical expression pattern of p16 in biopsy samples has been useful as part of a panel to distinguish adenocarcinomas arising from the endometrium from those arising from the endocervix. However, no information is available on the expression of p16 in uterine serous carcinoma (USC) or ovarian high-grade serous carcinoma that could be used for diagnostic purposes. Here, we retrospectively analyzed the immunohistochemical expression of p16 in 11 cases of USC (5 pure and 6 mixed… CONTINUE READING
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