Immunohistochemical localization of sulfhydryl oxidase correlates with disulfide crosslinking in the upper epidermis of rat skin

@article{Hashimoto2000ImmunohistochemicalLO,
  title={Immunohistochemical localization of sulfhydryl oxidase correlates with disulfide crosslinking in the upper epidermis of rat skin},
  author={Yukiko Hashimoto and Yasushi Suga and Shouichi Matsuba and Masayuki Mizoguchi and Kenji Takamori and J. T. Seitz and Hideoki Ogawa},
  journal={Archives of Dermatological Research},
  year={2000},
  volume={292},
  pages={570-572}
}
Striking morphological changes occur during the terminal stages of epidermal differentiation, such as the loss of major cellular organelles, the aggregation of keratin filaments and the formation of the cornified cell envelope (CCE). The CCE is a highly specialized structure in the cell periphery [1–3], and serves as a physical barrier for the organism and helps to maintain the structural integrity of the upper epidermis. The CCE is rendered insoluble by various post-translational modifications… CONTINUE READING