Immunohistochemical localization of Ca2+/calmodulin-dependent protein kinase II in rat brain and various tissues.

@article{Fukunaga1988ImmunohistochemicalLO,
  title={Immunohistochemical localization of Ca2+/calmodulin-dependent protein kinase II in rat brain and various tissues.},
  author={Koichi Fukunaga and Satoshi Goto and Eishichi Miyamoto},
  journal={Journal of neurochemistry},
  year={1988},
  volume={51 4},
  pages={1070-8}
}
Polyclonal antibodies against Ca2+/calmodulin-dependent protein kinase II (CaM kinase II) of rat brain were prepared by immunizing rabbits and then purified by antigen-affinity column. The antibodies which recognized both subunits of the enzyme with Mrs 49K and 60K were used for the study on the distribution of CaM kinase II in formalin-fixed, paraffin-embedded tissues. In the brain, a light-microscopic study demonstrated strong immunoreactivity in neuronal somata and dendrites and weak… CONTINUE READING
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