Immunohistochemical localization of metallothionein in chronic pancreatitis.

  title={Immunohistochemical localization of metallothionein in chronic pancreatitis.},
  author={Halina Milnerowicz and Monika Chmarek and Jerzy Rabczyński and Stanislaw Milnerowicz and Stanislaw Nabzdyk and Witold Knast},
  volume={29 1},
Metallothionein (MT) is a low-molecular weight intracellular protein, rich in sulfhydryl residues, and able to bind bivalent metals. MT, like Zn, is a component of the diversified elements of antioxidant system. Recent studies have shown that reactive oxygen species play a role in the pathogenesis and development of chronic pancreatitis. The aim of the study was to identify immunohistochemically (LSAB2-HRP; DAKOCytomation) the localization of metallothionein and to determine MT expression in 9… CONTINUE READING