Immunohistochemical localization of macrophages and microglia in the adult and developing mouse brain.

@article{Perry1985ImmunohistochemicalLO,
  title={Immunohistochemical localization of macrophages and microglia in the adult and developing mouse brain.},
  author={V Hugh Perry and D A Hume and Saimon Gordon},
  journal={Neuroscience},
  year={1985},
  volume={15 2},
  pages={313-26}
}
Macrophages and microglia in the developing and adult mouse brain have been identified by immunohistochemical localization of the macrophage-specific antigen F4/80 and monoclonal antibodies to the FcIgG1/2b (2.4G2) and type-three complement (Mac-1) receptors. In the adult mouse there are two classes of F4/80-positive cells; those associated with the choroid plexus, ventricles and leptomeninges and the microglia. The cells bearing Fc and complement receptors are indistinguishable, by their… CONTINUE READING
Highly Influential
This paper has highly influenced 14 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 224 extracted citations

Transcriptional control of microglia phenotypes in health and disease.

The Journal of clinical investigation • 2017
View 10 Excerpts
Highly Influenced

Origin of microglia: current concepts and past controversies.

Cold Spring Harbor perspectives in biology • 2015
View 4 Excerpts
Highly Influenced

Microglia: gatekeepers of central nervous system immunology.

Journal of leukocyte biology • 2009
View 7 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…