Immunohistochemical localization of N-acetylaspartate in rat brain.

  title={Immunohistochemical localization of N-acetylaspartate in rat brain.},
  author={John R. Moffett and M. A. Aryan Namboodiri and Charles B Cangro and Joseph H Neale},
  volume={2 3},
N-acetylaspartate (NAA) is one of the most prevalent compounds in the mammalian nervous system. As such, NAA largely contributes to the major peak on water-suppressed proton magnetic resonance spectra. Highly specific antibodies to NAA demonstrate that this compound is discretely localized in a substantial number of neurons throughout the extent of the rat CNS. N-acetylaspartylglutamate (NAAG) is a structurally related neuronal dipeptide which is less widely distributed than NAA. NAAG and NAA… CONTINUE READING

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