Immunohistochemical localization of estrogen receptors in human mammary carcinoma using antibodies to the receptor protein.

@article{Raam1982ImmunohistochemicalLO,
  title={Immunohistochemical localization of estrogen receptors in human mammary carcinoma using antibodies to the receptor protein.},
  author={Shanthi Raam and Edward M Nemeth and Hisashi Tamura and Donal Sean O'briain and Joseph L. Cohen},
  journal={European journal of cancer & clinical oncology},
  year={1982},
  volume={18 1},
  pages={1-12}
}
An immunofluorescent method has been developed for localizing estrogen receptors (ER) in frozen sections of human breast cancer biopsies which utilizes the biochemically well-characterized antibodies to the cytoplasmic ER of human breast cancer produced in rabbits. Frozen sections of sixteen breast cancer biopsies, in which the receptor content has been quantified using dextran-coated charcoal assay (DCC technique), were used to study the localization of ER. Two aspects of ER detection, namely… CONTINUE READING