Immunohistochemical localization of choline acetyltransferase during development and in Chats mutants of Drosophila melanogaster.

@article{Gorczyca1987ImmunohistochemicalLO,
  title={Immunohistochemical localization of choline acetyltransferase during development and in Chats mutants of Drosophila melanogaster.},
  author={Michael G. Gorczyca and Jeffrey C. Hall},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1987},
  volume={7 5},
  pages={1361-9}
}
The distribution of choline acetyltransferase (CAT) in the nervous system of Drosophila melanogaster was determined by indirect immunohistochemical procedures using a monoclonal antibody specific to the enzyme. Immunoreactivity was first detected in the nervous system of 16 hr embryos, and increased considerably by the end of embryogenesis. Neuropil was preferentially stained, though cell bodies could also be observed. Staining was prominent in the CNS of all 3 larval instars but decreased… CONTINUE READING

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