Immunohistochemical localization of blood-retinal barrier breakdown in human diabetics.

  title={Immunohistochemical localization of blood-retinal barrier breakdown in human diabetics.},
  author={Stanley A. Vinores and C Gadegbeku and Peter Anthony Campochiaro and William Richard Green},
  journal={The American journal of pathology},
  volume={134 2},
Localization of the site of blood-retinal barrier breakdown in diabetes has been controversial. It has been particularly difficult to make assessments in clinical material where the use of tracer materials may not be practical. In this study, immunohistochemical staining for albumin was performed on paraffin-embedded eyes from patients with no known ocular disease and those with various stages of diabetic retinopathy. No extravascular albumin was detected in the retina or retinal pigment… CONTINUE READING
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