Immunohistochemical localization of avian leukosis virus subgroup J in tissues from naturally infected chickens.

@article{Gharaibeh2001ImmunohistochemicalLO,
  title={Immunohistochemical localization of avian leukosis virus subgroup J in tissues from naturally infected chickens.},
  author={Saad Gharaibeh and Timothy A. Brown and Nancy L. Stedman and M Pantin},
  journal={Avian diseases},
  year={2001},
  volume={45 4},
  pages={992-8}
}
The tissue tropism of avian leukosis virus (ALV) subgroup J (ALV-J) was investigated in congenitally infected broiler chickens by an immunohistochemistry technique detecting gp85 viral glycoprotein. All organs examined contained detectable antigen. The most intense staining was in the adrenal gland, heart, kidney, and proventriculus. Intense staining for viral antigen in the heart may explain the ability of ALVs to cause cardiomyopathy. Although recent investigations failed to demonstrate… CONTINUE READING