Immunohistochemical localization of angiotensin II receptor and local renin-angiotensin system in human colonic mucosa.

@article{Hirasawa2002ImmunohistochemicalLO,
  title={Immunohistochemical localization of angiotensin II receptor and local renin-angiotensin system in human colonic mucosa.},
  author={Koki Hirasawa and Yoshihiko Sato and Yoshisuke Hosoda and Tastuo Yamamoto and Hiroyuki Hanai},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  year={2002},
  volume={50 2},
  pages={275-82}
}
Angiotensin II (Ang II) regulates water and sodium transport in renal tubules and gastrointestinal tract. Two types of Ang II receptors have been cloned, but their distributions have not been determined in human colon. In addition, tissue renin-angiotensin systems (RAS) are believed to exist and to regulate local actions in human colon. We studied by reverse transcription-polymerase chain reaction (RT-PCR) and immunohistochemistry (IHC) the presence and localization of Ang II receptors Type 1… CONTINUE READING