Immunohistochemical localization of NQO1 in epithelial dysplasia and neoplasia and in donor eyes.

@article{Schelonka2000ImmunohistochemicalLO,
  title={Immunohistochemical localization of NQO1 in epithelial dysplasia and neoplasia and in donor eyes.},
  author={L P Schelonka and David Siegel and Matthew W. Wilson and Alexander K Meininger and David D. Ross},
  journal={Investigative ophthalmology & visual science},
  year={2000},
  volume={41 7},
  pages={1617-22}
}
PURPOSE To examine the expression of NAD(P)H:quinone oxidoreductase 1 (NQO1, DT-diaphorase), a potential bioactivating enzyme for mitomycin C in corneal and conjunctival epithelial dysplasia and neoplasia and in normal tissues from human donor eyes, by immunohistochemistry. METHODS Formalin-fixed, paraffin-embedded sections of human donor eyes and tissue sections with histologic diagnoses of corneal and conjunctival epithelial dysplasia and neoplasia from the Eye Pathology Laboratory… CONTINUE READING

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