Immunohistochemical localisation of advanced glycation end products in pulmonary fibrosis.

@article{Matsuse1998ImmunohistochemicalLO,
  title={Immunohistochemical localisation of advanced glycation end products in pulmonary fibrosis.},
  author={Takeshi Matsuse and Eijiro Ohga and Sakiko Teramoto and Masashi Fukayama and Rie Nagai and Seikoh Horiuchi and Yasuomi Ouchi},
  journal={Journal of clinical pathology},
  year={1998},
  volume={51 7},
  pages={515-9}
}
AIM To investigate the presence and distribution of advanced glycation end products (AGE) in pulmonary fibrosis. METHODS Lung tissue samples obtained from seven necropsy cases with idiopathic pulmonary fibrosis and seven with normal pulmonary parenchyma were examined immunohistochemically with a monoclonal antibody specific for AGE: 6D12. We also tested three cases with diffuse alveolar damage. RESULTS All the specimens from cases with pulmonary fibrosis and diffuse alveolar damage showed… CONTINUE READING