Immunohistochemical galectin-3 expression in non-melanoma skin cancers.

  title={Immunohistochemical galectin-3 expression in non-melanoma skin cancers.},
  author={Nilgun Kapucuoğlu and Pinar Yuksel Basak and Sema Bircan and Sevda Sert and Vahide Baysal Akkaya},
  journal={Pathology, research and practice},
  volume={205 2},
Galectin-3 is a ss-galactoside-binding lectin. It participates in a variety of normal and pathologic processes, including cancer progression. In this study, we evaluated the pattern of expression of galectin-3 in cutaneous squamous cell carcinoma (SCC) and basal cell carcinoma (BCC), and its correlation with the grade of differentiation in SCC and tumor size. Galectin-3 expression was evaluated by immunohistochemistry in 31 SCCs, 30 BCCs, and 29 non-tumoral skin samples. Galectin-3 expression… CONTINUE READING


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