Immunohistochemical expression of two members of the GDNF family of growth factors and their receptors in the olfactory system.

@article{Maroldt2005ImmunohistochemicalEO,
  title={Immunohistochemical expression of two members of the GDNF family of growth factors and their receptors in the olfactory system.},
  author={Heike Maroldt and Tala Kaplinovsky and Anne Marie Cunningham},
  journal={Journal of neurocytology},
  year={2005},
  volume={34 3-5},
  pages={
          241-55
        }
}
The glial cell line-derived (GDNF) family of trophic factors, GDNF, neurturin, persephin and artemin, are known to support the survival and regulate differentiation of many neuronal populations, including peripheral autonomic, enteric and sensory neurons. Members of this family of related ligands bind to specific GDNF family receptor (GFR) proteins, which complex and signal through the Ret receptor tyrosine kinase. We showed previously that GDNF protein was detectable in olfactory sensory… CONTINUE READING