Immunohistochemical expression of matrix metalloproteinases 1, 2, 9, and 14 in dermatofibrosarcoma protuberans and common fibrous histiocytoma (dermatofibroma).

@article{Weinrach2004ImmunohistochemicalEO,
  title={Immunohistochemical expression of matrix metalloproteinases 1, 2, 9, and 14 in dermatofibrosarcoma protuberans and common fibrous histiocytoma (dermatofibroma).},
  author={David M Weinrach and Kim L Wang and Elizabeth Louise Wiley and William Bradlyn Laskin},
  journal={Archives of pathology & laboratory medicine},
  year={2004},
  volume={128 10},
  pages={1136-41}
}
CONTEXT Common fibrous histiocytoma (cFH) or dermatofibroma and dermatofibrosarcoma protuberans (DFSP) are 2 spindle cell mesenchymal tumors that are distinguished in part by their microscopic growth patterns and clinically by the greater propensity for DFSP to recur. Matrix metalloproteinases (MMPs) potentially play a role in modulating the growth patterns of cFH and DFSP by remodeling the extracellular matrix. OBJECTIVE To evaluate the immunohistochemical (IHC) expression of MMP-1, MMP-2… CONTINUE READING