Immunohistochemical expression of VEGF and VEGF receptors in nasal polyps as compared to normal turbinate mucosa

@article{Wittekindt2002ImmunohistochemicalEO,
  title={Immunohistochemical expression of VEGF and VEGF receptors in nasal polyps as compared to normal turbinate mucosa},
  author={Claus Wittekindt and Alexander Hess and Wilhelm Bloch and Suleiman Sultanie and Olaf Michel},
  journal={European Archives of Oto-Rhino-Laryngology},
  year={2002},
  volume={259},
  pages={294-298}
}
The factors involved in the development of chronic inflammation and edema in nasal polyps remain to be clarified. The expression of vascular endothelial growth factor (VEGF) has been described in plasma cells, suggesting that plasma cells may play a major role in the development of edema in nasal polyps through the production of VEGF. We performed immunohistochemical analysis using specific antibodies to VEGF and to the known VEGF receptors, VEGFR-1 and VEGFR-2, on paraffin sections of human… CONTINUE READING