Immunohistochemical expression of CA 125 in endometrial adenocarcinoma: correlation of antigen expression with metastatic potential.

@article{Berchuck1989ImmunohistochemicalEO,
  title={Immunohistochemical expression of CA 125 in endometrial adenocarcinoma: correlation of antigen expression with metastatic potential.},
  author={Andrew Berchuck and Andrew Patrick Soisson and Daniel L. Clarke-Pearson and John T. Soper and Cinda M. Boyer and Ronald Kinney and Kenneth McCarty and Robert C. Bast},
  journal={Cancer research},
  year={1989},
  volume={49 8},
  pages={2091-5}
}
Immunohistochemical localization of CA 125 using murine monoclonal antibody OC 125 was performed on fresh frozen tissue from 44 endometrial adenocarcinomas and 26 benign endometria. Immunohistochemical evaluation incorporated both intensity and distribution of staining (CA 125 HSCORE). Thirty-seven cancers (84%) and 23 benign endometria (88%) expressed immunohistochemically detectable CA 125. Staining was confined to epithelial cells and was present both on the cell membrane and in the… CONTINUE READING
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Characterization of the CA 125 antigen associated with human epithelial ovarian cancers

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