Immunohistochemical expression of C-reactive protein in squamous cell carcinoma of the esophagus - significance as a tumor marker.

@article{Nozoe2003ImmunohistochemicalEO,
  title={Immunohistochemical expression of C-reactive protein in squamous cell carcinoma of the esophagus - significance as a tumor marker.},
  author={Tadahiro Nozoe and Daisuke Korenaga and Motonori Futatsugi and Hiroshi Saeki and Yoshihiko Maehara and Keizo Sugimachi},
  journal={Cancer letters},
  year={2003},
  volume={192 1},
  pages={89-95}
}
C-reactive protein (CRP) is a prototype acute phase protein which has been known to be synthesized in hepatocytes. Although serum elevation of CRP has been reported to be an indicator of the unfavorable outcome of the patients in some malignant tumors, the expression of the protein in carcinoma cells has not been investigated. The aim of the current study was to assess the immunohistochemical expression of CRP in squamous cell carcinoma (SCC) of the esophagus and to find its biological… CONTINUE READING