Immunohistochemical evidence of the presence of aromatase P450 in the rat hypophysis

  title={Immunohistochemical evidence of the presence of aromatase P450 in the rat hypophysis},
  author={Jos{\'e} A Carretero and G. Vazquez and Enrique J. Blanco and Manuel I Maldonado Rubio and Marta Santos and Agust{\'i}n Mart{\'i}n-Clavijo and Josep Llu{\'i}s Torres and Ricardo Manuel V{\'a}zquez},
  journal={Cell and Tissue Research},
In order to analyze whether aromatase is present in the hypophysis of adult rats, we have performed an immunohistochemical study in young adult male and female rats. Our study has revealed that the hypophysis of adult rats contains aromatase, although marked differences are found between the sexes. The hypophyses of male rats have cells immunoreactive for the enzyme, 34.40% of these hypophyseal cells showing reaction. By contrast, cells from female rats show very little reaction, only 0.84% of… CONTINUE READING

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