Immunohistochemical evidence of disease recurrence after liver transplantation for primary biliary cirrhosis.

@article{Water1996ImmunohistochemicalEO,
  title={Immunohistochemical evidence of disease recurrence after liver transplantation for primary biliary cirrhosis.},
  author={Judy Van de Water and Lauren B. Gerson and Linda D. Ferrell and John R. Lake and Ross L Coppel and Kenneth P. Batts and Russell H. Wiesner and M Eric Gershwin},
  journal={Hepatology},
  year={1996},
  volume={24 5},
  pages={1079-84}
}
Whether primary biliary cirrhosis (PBC) recurs after liver transplantation has remained an interesting and controversial issue; rejection, viral hepatitis, and drug effects all may mimic recurrent PBC histologically and biochemically. Furthermore, reliable clinical criteria for PBC recurrence are lacking. In this study, the issue of disease recurrence using a well-characterized monoclonal antibody (MAb), C355.1, that reacts with the immunodominant mitochondrial autoantigen of PBC (pyruvate… CONTINUE READING

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