Immunohistochemical evaluation of the microvascular density through the expression of TGF-beta (CD 105/endoglin) and CD 34 receptors and expression of the vascular endothelial growth factor (VEGF) in oligodendrogliomas.

@article{Netto2008ImmunohistochemicalEO,
  title={Immunohistochemical evaluation of the microvascular density through the expression of TGF-beta (CD 105/endoglin) and CD 34 receptors and expression of the vascular endothelial growth factor (VEGF) in oligodendrogliomas.},
  author={Gabriel Corteze Netto and Cristina Birlem Bleil and Arlete Hilbig and L{\'i}gia Maria Barbosa Coutinho},
  journal={Neuropathology : official journal of the Japanese Society of Neuropathology},
  year={2008},
  volume={28 1},
  pages={17-23}
}
Angiogenesis has been proposed as essential for the growth of solid tumors. The determinants of this process, the growth factors and the vascular endothelial receptors have brought a potential in the tumor prognostic determination as well as perspectives of "targets" for antiangiogenic therapy. In oligodendrogliomas (OL), angiogenesis is little known and/or has generated conflicting results. In order to clarify angiogenesis in OL, we have evaluated the immunohistochemical expression of vascular… CONTINUE READING
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