Immunohistochemical evaluation of dystrophin expression in small round cell tumors of childhood.

@article{Pinto1993ImmunohistochemicalEO,
  title={Immunohistochemical evaluation of dystrophin expression in small round cell tumors of childhood.},
  author={Ant{\^o}nio Raimundo Pinto and Daniel John Paslawski and Harvey B. Sarnat and David M Parham},
  journal={Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc},
  year={1993},
  volume={6 6},
  pages={
          679-83
        }
}
Dystrophin, the protein product of the Duchenne muscular dystrophy locus, is a major component of the subsarcolemmal cytoskeleton in skeletal muscle cells and is a relatively muscle specific protein. We evaluated, retrospectively, the expression of dystrophin in 23 small round cell tumors of childhood including: 9 rhabdomyosarcomas, 4 neuroblastomas, 1 ganglioneuroblastoma, 2 small noncleaved cell lymphomas, 1 lymphoblastic lymphoma, 2 medulloblastomas, 2 primitive neuroectodermal tumors, 1… CONTINUE READING