Immunohistochemical evaluation of cathepsin D expression in colorectal cancer.

@article{Chabowski2001ImmunohistochemicalEO,
  title={Immunohistochemical evaluation of cathepsin D expression in colorectal cancer.},
  author={Adrian Chabowski and Mariola Sulkowska and Miko Sulkowski and Waldemar Famulski and Elżbieta Skrzydlewska and Wojciech Kisielewski},
  journal={Folia histochemica et cytobiologica},
  year={2001},
  volume={39 2},
  pages={153-4}
}
Cathepsin D is one of the main proteolytic enzymes contributing to the development of cancer. The aim of the present study was to evaluate the expression of cathepsin D in 48 colorectal adenocarcinomas at pT3 stage of clinical advancement and G2 histologic grade. The correlation between cathepsin D expression, anatomo-clinical advancement and the presence of chosen anatomo-clinical properties of the tumours was also analysed. Formalin-fixed and paraffin-embedded tissues were investigated with… CONTINUE READING

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