Immunohistochemical dystrophin reaction in synaptic regions.

  title={Immunohistochemical dystrophin reaction in synaptic regions.},
  author={Teruhisa Miike and Mari Miyatake and J E Zhao and Kowashi Yoshioka and Makoto Uchino},
  journal={Brain & development},
  volume={11 5},
To investigate the functional significance of dystrophin, we studied various tissues of control and mdx mice, and rats immunohistochemically, using anti-dystrophin antibodies. In control animals, we observed the immunohistochemical localization of dystrophin in synaptic regions such as neuromuscular junctions, the cornea and outer plexiform layer of the retina, the taste buds and neurons in the brain, as well as on the surface membrane of skeletal, cardiac and smooth muscle fibers. In mdx mice… CONTINUE READING