Immunohistochemical distinction of follicular thyroid adenomas and follicular carcinomas.

  title={Immunohistochemical distinction of follicular thyroid adenomas and follicular carcinomas.},
  author={Paul C Bryson and Carol G. Shores and C. Frederick Hart and Leigh B. Thorne and Mihir R. Patel and Luke M Richey and Alexander A Farag and Adam M. Zanation},
  journal={Archives of otolaryngology--head & neck surgery},
  volume={134 6},
OBJECTIVES To use immunohistochemical (IHC) evaluation of proteins encoded by genes that were differentially expressed in follicular thyroid adenomas (FAs) vs follicular thyroid carcinomas (FTCs) to distinguish benign vs malignant follicular thyroid lesions. Multiple gene microarray studies suggest that benign and malignant follicular thyroid neoplasms have different gene expression profiles. DESIGN Immunohistochemical analysis of thyroid neoplasms, including FA (n = 62), FTC (n = 62), and… CONTINUE READING
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