Immunohistochemical detection of human Natural Killer cell like immuno-reactivity in human pituitary adenomas, using monoclonal antibody NK-1

@article{Sanno1997ImmunohistochemicalDO,
  title={Immunohistochemical detection of human Natural Killer cell like immuno-reactivity in human pituitary adenomas, using monoclonal antibody NK-1},
  author={Naoko Sanno and Johbu Itoh and Akira Teramoto and Yoshiko Itoh and Sadaaki Hori and Robert Yoshiyuki Osamura},
  journal={Journal of Neuro-Oncology},
  year={1997},
  volume={35},
  pages={29-38}
}
Natural killer (NK) cells are specialized lymphocytes which arecharacterized as non-T and non-B cells, as they lack classic T and B cellsurface markers. Recently, NK like immunoreactivity has been identified inendocrine and neuronal tissues as well as in the tumors derived from theneuroectoderm and neuroendocrine system. We examined the expression of NK-1like immunoreactivity in 6 normal pituitary glands and in 55 cases ofneoplastic pituitaries (16 growth hormone (GH) producing adenomas… CONTINUE READING
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