Immunohistochemical detection of EGFR mutation using mutation-specific antibodies in lung cancer.

Abstract

PURPOSE Patients with mutations of epidermal growth factor receptor (EGFR) receive more benefit from EGFR-tyrosine kinase inhibitor treatment. However, usually such treatment is used to treat advanced lung cancer and only small biopsy samples are available for mutational analysis. We used immunohistochemistry to examine recently developed antibodies… (More)
DOI: 10.1158/1078-0432.CCR-10-0129

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Cite this paper

@article{Kitamura2010ImmunohistochemicalDO, title={Immunohistochemical detection of EGFR mutation using mutation-specific antibodies in lung cancer.}, author={Atsuko Kitamura and Waki Hosoda and Eiichi Sasaki and Tetsuya Mitsudomi and Yasushi Yatabe}, journal={Clinical cancer research : an official journal of the American Association for Cancer Research}, year={2010}, volume={16 13}, pages={3349-55} }