Immunohistochemical detection of ARID1A in colorectal carcinoma: loss of staining is associated with sporadic microsatellite unstable tumors with medullary histology and high TNM stage.

@article{Ye2014ImmunohistochemicalDO,
  title={Immunohistochemical detection of ARID1A in colorectal carcinoma: loss of staining is associated with sporadic microsatellite unstable tumors with medullary histology and high TNM stage.},
  author={Jiqing Ye and Yi Zhou and Martin R Weiser and Mithat G{\"o}nen and Liying Zhang and Tushar Samdani and Ruben Bacares and Deborah F Delair and Sinisa Ivelja and Efsevia Vakiani and David S. Klimstra and Robert A Soslow and Jinru Shia},
  journal={Human pathology},
  year={2014},
  volume={45 12},
  pages={
          2430-6
        }
}
AT-rich interactive domain-containing protein 1A (ARID1A), a chromatin remodeling gene recently discovered to be a tumor suppressor in ovarian cancers, has been found to be mutated at low frequencies in many other tumors including colorectal carcinoma (CRC). An association between ARID1A alteration and DNA mismatch repair (MMR) deficiency has been implicated; understanding this association may facilitate the understanding of the role of ARID1A in the various tumors. In this pilot study, we… CONTINUE READING
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Loss ofARID 1 Aexpression and its relationship with PI 3 KAkt pathway alterations , TP 53 and microsatellite instability in endometrial cancer

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Loss ofARID 1 Aexpression and its relationship with PI 3 KAkt pathway alterations , TP 53 and microsatellite instability in endometrial cancer

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Loss ofARID1Aexpression and its relationship with PI3K-Akt pathway alterations, TP53 and microsatellite instability in endometrial cancer

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  • Mod Pathol ;135:611-23
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