• DOI:10.1161/01.RES.66.4.900
Corpus ID: 22894368

Immunohistochemical demonstration of human cardiac innervation before and after transplantation.

@article{Wharton1990ImmunohistochemicalDO,
  title={Immunohistochemical demonstration of human cardiac innervation before and after transplantation.},
  author={J. Wharton and J. Polak and L. Gordon and N. Banner and D. Springall and M. Rose and A. Khagani and J. Wallwork and M. Yacoub},
  journal={Circulation research},
  year={1990},
  volume={66 4},
  pages={
          900-12
        }
}

• J. Wharton, J. Polak, +6 authors M. Yacoub
• Published 1990
• Biology, Medicine
• Circulation research

Knowledge about the distribution and origins of peptide-containing nerves in the innervated and transplanted heart is lacking. Immunohistochemical and histochemical techniques were used to visualize human cardiac innervation before and after transplantation. In the recipient heart cardiac nerve fibers and fascicles displayed immunoreactivity for general neural (protein gene product 9.5 and synaptophysin) and Schwann cell markers (S-100). A major proportion of cardiac nerves displayed… Expand

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