Immunohistochemical demonstration of bone morphogenetic protein-2 and transforming growth factor-beta in the ossification of the posterior longitudinal ligament of the cervical spine.

@article{Kawaguchi1992ImmunohistochemicalDO,
  title={Immunohistochemical demonstration of bone morphogenetic protein-2 and transforming growth factor-beta in the ossification of the posterior longitudinal ligament of the cervical spine.},
  author={Hideaki Kawaguchi and Takahide Kurokawa and Yuichi Hoshino and Hiroto Kawahara and Etsuro Ogata and Tadami Matsumoto},
  journal={Spine},
  year={1992},
  volume={17 3 Suppl},
  pages={S33-6}
}
To clarify the mechanism of ossification of the posterior longitudinal ligament, immunohistochemical localization of bone morphogenetic protein-2 and transforming growth factor-beta was examined using surgical specimens of ligament tissues from an affected patient. Two polyclonal antibone morphogenetic protein-2 antibodies and an anti-human transforming growth factor-beta antibody were used as primary antibodies. Bone morphogenetic protein-2 and transforming growth factor-beta were present in… CONTINUE READING
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