Immunohistochemical demonstration of androgen receptor in breast cancer and its relationship to other prognostic factors.

Abstract

Androgen actions and androgen receptors (ARs) have been described in human breast cancer cells both in vivo and in vitro. With the use of a new monoclonal anti-AR antibody, AR was immunohistochemically demonstrated in 76 primary breast cancers. Positive immunostaining was found in 79 percent of tumours. Benign ductal epithelium was often AR-positive whereas… (More)

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