Immunohistochemical co-expression status of cytokeratin 5/6, androgen receptor, and p53 as prognostic factors of adjuvant chemotherapy for triple negative breast cancer

@article{Maeda2015ImmunohistochemicalCS,
  title={Immunohistochemical co-expression status of cytokeratin 5/6, androgen receptor, and p53 as prognostic factors of adjuvant chemotherapy for triple negative breast cancer},
  author={Tetsuyo Maeda and Yoko Nakanishi and Yukari Hirotani and Fumi Fuchinoue and Katsuhisa Enomoto and Kenichi Sakurai and Sadao Amano and Norimichi Nemoto},
  journal={Medical Molecular Morphology},
  year={2015},
  volume={49},
  pages={11-21}
}
Triple negative breast cancer (TNBC) is immunohistochemically characterised by the lack of expression of the estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor type 2 (HER2). TNBC is known for its poor prognosis and high recurrence probability. There is no effective targeted treatment for TNBC, but only adjuvant chemotherapies. There are two TNBC subtypes, basal-like and non-basal-like, which are defined based on positive cytokeratin (CK) 5/6 and/or… CONTINUE READING
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Cytokeratin 20 Med Mol Morphol (2016

  • M Inanc, M Ozkan, +7 authors F Elmali
  • Med Oncol
  • 2014
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