Immunohistochemical characterization of oral mucosal lesions in cats with chronic gingivostomatitis.

  title={Immunohistochemical characterization of oral mucosal lesions in cats with chronic gingivostomatitis.},
  author={R. J. Harley and Timothy John Gruffydd-Jones and M. J. Day},
  journal={Journal of comparative pathology},
  volume={144 4},
Histological and immunohistochemical studies were performed on samples of the glossopalatine mucosa from 30 cats with feline chronic gingivostomatitis (FCGS). Immunohistochemical labelling and computer-assisted morphometric analysis were used to identify expression of CD3, CD4, CD8, CD79a, IgG, IgM, IgA, leucocyte antigen 1 (L1) and class II molecules of the major histocompatibility complex (MHC) in tissue sections. Mast cells were detected by toluidine blue staining. The microscopical lesions… CONTINUE READING


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