Immunohistochemical characterisation of classical scrapie neuropathology in sheep.

  title={Immunohistochemical characterisation of classical scrapie neuropathology in sheep.},
  author={Enric Vidal and Cristina Ac{\'i}n and Laia Foradada and Marta Monz{\'o}n and Mercedes Roc{\'i}o Gonzales M{\'a}rquez and Eva Monle{\'o}n and Mart{\'i} Batlle Pumarola and Juan Jos{\'e} Badiola and R. G. Bolea},
  journal={Journal of comparative pathology},
  volume={141 2-3},
Neuroinflammation elicited by PrP(res) (resistant prion protein [PrP]) deposits in the central nervous system (CNS) has been shown to involve cellular and oxidative stress responses in bovine spongiform encephalopathy (BSE) as well as in several murine models of transmissible spongiform encephalopathy (TSE). Additionally, deregulation of water homeostasis has been suggested to be a further component of the spongiform changes observed in TSEs. The aim of the present study was to characterize the… CONTINUE READING
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