Immunohistochemical assessment for estrogen receptor and progesterone receptor status in breast cancer: Analysis for a cut-off point as the predictor for endocrine therapy

@article{Ogawa2004ImmunohistochemicalAF,
  title={Immunohistochemical assessment for estrogen receptor and progesterone receptor status in breast cancer: Analysis for a cut-off point as the predictor for endocrine therapy},
  author={Yoshinari Ogawa and Takuya Moriya and Yasuyuki Kato and Mitsue Oguma and Katsumi Ikeda and Tsutomua Takashima and Bunzo Nakata and Tetsuro Ishikawa and Kosei Hirakawa},
  journal={Breast Cancer},
  year={2004},
  volume={11},
  pages={267-275}
}
  • Yoshinari Ogawa, Takuya Moriya, +6 authors Kosei Hirakawa
  • Published in Breast cancer 2004
  • Medicine
  • Breast Cancer
  • BackgroundAn immunohistochemical (IHC) method is commonly used for determining estrogen receptor (ER) and progesterone receptor (PR) status in breast cancer. However, the proper cut-off points of IHC have not been established. Cut-off points for ER and PR status as predictive factors for endocrine therapy are needed.MethodsA total of 249 cases of female breast cancer were enrolled. ER and PR status by IHC were analyzed using the proportion of stained cells and staining intensity by Allred’s… CONTINUE READING

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