Immunohistochemical analysis of sympathetic involvement in the SOD1-G93A transgenic mouse model of amyotrophic lateral sclerosis.

@article{Kandinov2013ImmunohistochemicalAO,
  title={Immunohistochemical analysis of sympathetic involvement in the SOD1-G93A transgenic mouse model of amyotrophic lateral sclerosis.},
  author={Boris Kandinov and Nikolaos Grigoriadis and Olga Touloumi and Vivian Drory and Daniel Offen and Amos D. Korczyn},
  journal={Amyotrophic lateral sclerosis & frontotemporal degeneration},
  year={2013},
  volume={14 5-6},
  pages={424-33}
}
Amyotrophic lateral sclerosis (ALS) is a progressive and fatal disorder caused by degeneration of motor neurons in the cerebral cortex, brainstem and spinal cord. Several clinical reports indicated sympathetic and parasympathetic dysfunction in ALS patients. In addition, we have recently reported elevated heart rate and blood pressure in transgenic (TG… CONTINUE READING