Immunohistochemical analysis of ageing human B and T cell populations reveals an age-related decline of CD8 T cells in spleen but not gut-associated lymphoid tissue (GALT).

@article{Banerjee2000ImmunohistochemicalAO,
  title={Immunohistochemical analysis of ageing human B and T cell populations reveals an age-related decline of CD8 T cells in spleen but not gut-associated lymphoid tissue (GALT).},
  author={Manish Banerjee and Jeremy David Sanderson and J S Spencer and Deborah Dunn-Walters},
  journal={Mechanisms of ageing and development},
  year={2000},
  volume={115 1-2},
  pages={85-99}
}
It is thought that senescence of the immune system is responsible, at least in part, for many health problems associated with ageing. Previous studies on changes in lymphocyte composition have used flow cytometry to study peripheral blood lymphocytes (PBL's), or cells isolated from rodent tissue, and have yielded conflicting results. We have used… CONTINUE READING