Immunohistochemical Profile of Acute Cellular Rejection in Renal Allograft

  title={Immunohistochemical Profile of Acute Cellular Rejection in Renal Allograft},
  author={Seung Woon Byun and E Yu and S K Park and Duck Jong Han and Young Mee Cho},
Background : We wanted to find an adjunctive marker(s) in renal allograft biopsies for predicting acute cellular rejection (ACR), and so the expression patterns of immune-related molecules were compared between ACR, borderline ACR and non-ACR cases. Methods : The expression patterns of Fas ligand (FasL), HLA-DR, granzyme B, caspase-3, CD56, interferon stimulated growth factor-3 (ISGF-3), and CD53 were assessed via immunohistochemical study in 75 allograft biopsies from patients with ACR (n=19… CONTINUE READING