Immunohistochemical Analysis of Langerin in Langerhans Cell Histiocytosis and Pulmonary Inflammatory and Infectious Diseases

@article{Sholl2007ImmunohistochemicalAO,
  title={Immunohistochemical Analysis of Langerin in Langerhans Cell Histiocytosis and Pulmonary Inflammatory and Infectious Diseases},
  author={L. Sholl and J. Hornick and J. Pinkus and G. Pinkus and R. Padera},
  journal={The American Journal of Surgical Pathology},
  year={2007},
  volume={31},
  pages={947-952}
}
  • L. Sholl, J. Hornick, +2 authors R. Padera
  • Published 2007
  • Medicine
  • The American Journal of Surgical Pathology
  • Pulmonary Langerhans cell histiocytosis (LCH) is an idiopathic condition affecting predominantly adult smokers. Histologically, LCH is characterized by a nodular, interstitial proliferation of Langerhans cells around the distal airways with associated eosinophils, lymphocytes, and macrophages. Associated findings, such as fibrosis, emphysematous change, and bronchiolitis can be reminiscent of other interstitial lung diseases. The markers CD1a and S100 have traditionally been used to distinguish… CONTINUE READING
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