Immunoglobulins IgG1, IgM and IgA: a synergistic team influencing survival in sepsis.

@article{BermejoMartin2014ImmunoglobulinsII,
  title={Immunoglobulins IgG1, IgM and IgA: a synergistic team influencing survival in sepsis.},
  author={Jesus F Bermejo-Martin and Ana Rodriguez-Fernandez and Rub{\'e}n Herr{\'a}n-Monge and David Andaluz-Ojeda and Arturo Muriel-Bomb{\'i}n and Pedro Merino and Marta Mar{\'i}a Garc{\'i}a-Garc{\'i}a and Rafael Citores and Francisco Jos{\'e} Varela Gand{\'i}a and R. Almansa and J{\'u}lia Mart{\'i}­nez Blanco},
  journal={Journal of internal medicine},
  year={2014},
  volume={276 4},
  pages={
          404-12
        }
}
OBJECTIVE The impact of endogenous immunoglobulin isotypes on the prognosis of patients with severe sepsis has not been sufficiently explored. The aim of this study was to evaluate the association between immunoglobulin levels in plasma and survival in patients with this condition. DESIGN AND PATIENTS A prospective multicentre cohort study was conducted. A total of 172 adult patients admitted to the intensive care unit (ICU) with severe sepsis or septic shock were recruited. Patients were… CONTINUE READING
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