Immunoglobulin treatment ameliorates murine myocarditis associated with reduction of neurohumoral activity and improvement of extracellular matrix change.

@article{Kishimoto2000ImmunoglobulinTA,
  title={Immunoglobulin treatment ameliorates murine myocarditis associated with reduction of neurohumoral activity and improvement of extracellular matrix change.},
  author={Chiharu Kishimoto and Nami Takamatsu and H Kawamata and Hiroyuki Shinohara and Hiroshi Ochiai},
  journal={Journal of the American College of Cardiology},
  year={2000},
  volume={36 6},
  pages={1979-84}
}
OBJECTIVES We examined effects of immunoglobulin on murine myocarditis induced by encephalomyocarditis virus, not pathogenic to humans, and analyzed the plasma cytokine and catecholamine levels and the changes of the extracellular matrix with or without the treatment. BACKGROUND We have previously shown that immunoglobulin therapy suppressed murine coxsackievirus B3 myocarditis by an antiviral effect. However, it is not yet determined whether beneficial effects of immunoglobulin for… CONTINUE READING