Immunoglobulin superfamily members play an important role in the mosquito immune system.

  title={Immunoglobulin superfamily members play an important role in the mosquito immune system.},
  author={Lindsey S Garver and Zhiyong Xi and George Dimopoulos},
  journal={Developmental and comparative immunology},
  volume={32 5},
Immunoglobulin superfamily (IgSF) proteins are known for their ability to specifically recognize and adhere to other molecules, mediating cell-surface reception and pathogen recognition. Mammalian IgSF proteins such as antibodies are among the best characterized molecules of the immune system; in contrast, the involvement of invertebrate IgSF members in immunity has not been broadly studied. Analysis of the predicted Anopheles gambiae transcriptome identified 138 proteins that have at least one… CONTINUE READING


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