• DOI:10.1038/252602A0
Corpus ID: 4157356

Immunoglobulin of T lymphoma cells is an integral membrane protein

@article{Haustein1974ImmunoglobulinOT,
  title={Immunoglobulin of T lymphoma cells is an integral membrane protein},
  author={D. Haustein and J. Marchalonis and MICHAEL J. Crumpton},
  journal={Nature},
  year={1974},
  volume={252},
  pages={602-604}
}

D. Haustein, J. Marchalonis, MICHAEL J. Crumpton

Published 1974

Chemistry, Medicine

Nature

IMMUNOGLOBULINS, predominantly 7S IgM molecules (molecular weight ∼ 200,000), are associated with the plasma membranes of lymphocytes1–3 and considerable evidence suggests that these proteins function as receptors for antigen4–6. If these molecules are themselves integral parts of the lymphocyte membrane or are strongly associated with integral proteins they may transmit antigen-induced signals through the membrane and initiate cell activation. It has been proposed that the antigen-combining… CONTINUE READING

View on Springer

ncbi.nlm.nih.gov

Save to Library

Create Alert

Cite

Launch Research Feed