Immunoglobulin of T lymphoma cells is an integral membrane protein

@article{Haustein1974ImmunoglobulinOT,
  title={Immunoglobulin of T lymphoma cells is an integral membrane protein},
  author={D. Haustein and J. Marchalonis and MICHAEL J. Crumpton},
  journal={Nature},
  year={1974},
  volume={252},
  pages={602-604}
}
  • D. Haustein, J. Marchalonis, MICHAEL J. Crumpton
  • Published 1974
  • Chemistry, Medicine
  • Nature
  • IMMUNOGLOBULINS, predominantly 7S IgM molecules (molecular weight ∼ 200,000), are associated with the plasma membranes of lymphocytes1–3 and considerable evidence suggests that these proteins function as receptors for antigen4–6. If these molecules are themselves integral parts of the lymphocyte membrane or are strongly associated with integral proteins they may transmit antigen-induced signals through the membrane and initiate cell activation. It has been proposed that the antigen-combining… CONTINUE READING
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    References

    SHOWING 1-10 OF 15 REFERENCES
    Membrane immunoglobulins and antigen receptors on B and T lymphocytes.
    • N. Warner
    • Biology, Medicine
    • Advances in immunology
    • 1974
    • 353
    Cell-surface immunoglobulin human thymus cells and its biosynthesis in vitro.
    • C. Moroz, Y. Hahn
    • Medicine, Chemistry
    • Proceedings of the National Academy of Sciences of the United States of America
    • 1973
    • 38
    • PDF
    ISOLATION AND PARTIAL CHARACTERIZATION OF LYMPHOCYTE SURFACE IMMUNOGLOBULINS
    • 238
    • PDF
    A RECEPTOR FOR ANTIBODY ON B LYMPHOCYTES
    • 387
    • PDF
    INHIBITION OF A T-CELL-DEPENDENT IMMUNE RESPONSE IN VITRO BY THYMOMA CELL IMMUNOGLOBULIN
    • 24
    • PDF