Immunoglobulin-binding domains: Protein L from Peptostreptococcus magnus.
@article{Housden2003ImmunoglobulinbindingDP, title={Immunoglobulin-binding domains: Protein L from Peptostreptococcus magnus.}, author={Nicholas G. Housden and Steven L Harrison and S E Roberts and Jennifer A. Beckingham and Marc Graille and Enrico A. Stura and Michael G. Gore}, journal={Biochemical Society transactions}, year={2003}, volume={31 Pt 3}, pages={ 716-8 } }
Protein L is a multidomain cell-wall protein isolated from Peptostreptococcus magnus. It belongs to a group of proteins that contain repeated domains that are able to bind to Igs without stimulating an immune response, the most characterized of this group being Protein A ( Staphylococcus aureus ) and Protein G ( Streptococcus ). Both of these proteins bind predominantly to the interface of C(H)2-C(H)3 heavy chains, while Protein L binds exclusively to the V(L) domain of the kappa -chain. The…
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