Immunoglobulin Replacement Therapy in Secondary Hypogammaglobulinemia

  title={Immunoglobulin Replacement Therapy in Secondary Hypogammaglobulinemia},
  author={Nicol{\`o} Compagno and Giacomo Malipiero and Francesco Cinetto and Carlo Agostini},
  booktitle={Front. Immunol.},
Immunoglobulin (Ig) replacement therapy dramatically changed the clinical course of primary hypogammaglobulinemias, significantly reducing the incidence of infectious events. Over the last two decades its use has been extended to secondary antibody deficiencies, particularly those related to hematological disorders as lymphoproliferative diseases (LPDs) and multiple myeloma. In these malignancies, hypogammaglobulinemia can be an intrinsic aspect of the disease or follow chemo-immunotherapy… CONTINUE READING
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