Immunoglobulin G subclass antibody responses of mice to influenza virus antigens given in different forms.

@article{Balkovic1987ImmunoglobulinGS,
  title={Immunoglobulin G subclass antibody responses of mice to influenza virus antigens given in different forms.},
  author={E. S. Balkovic and J A Florack and Howard R. Six},
  journal={Antiviral research},
  year={1987},
  volume={8 3},
  pages={151-60}
}
Total IgG and IgG subclass antibody responses in mice were studied after infection with virulent and non-virulent influenza viruses, and after vaccination with inactivated whole virus or purified surface glycoproteins (HANA-flu). Infection induced high IgG2a, low IgG1 and IgG2b, and very low IgG3 levels of antibody in serum. Whole virus vaccine induced high IgG2a, moderate IgG2b, and very low IgG1 and IgG3 levels of antibody. In marked contrast, HANA-flu preparations induced high IgG1, low… CONTINUE READING