Immunoglobulin G subclass and antibody avidity responses in Malian children immunized with Plasmodium falciparum apical membrane antigen 1 vaccine candidate FMP2.1/AS02A

@inproceedings{Berry2019ImmunoglobulinGS,
  title={Immunoglobulin G subclass and antibody avidity responses in Malian children immunized with Plasmodium falciparum apical membrane antigen 1 vaccine candidate FMP2.1/AS02A},
  author={Andrea A Berry and Eric R Gottlieb and Bour{\'e}ma Kouriba and Issa Diarra and Mahamadou A Thera and Sheetij Dutta and Drissa Coulibaly and Amed Ouattara and Amadou Niangaly and Abdoulaye Kassoum Kone and Karim Traore and Youssouf Tolo and Vladimir Mishcherkin and Lorraine A. Soisson and Carter L. Diggs and William C Blackwelder and Matthew B Laurens and Marcelo B. Sztein and Ogobara K. Doumbo and Christopher V. Plowe and Kirsten E. Lyke},
  booktitle={Malaria Journal},
  year={2019}
}
BackgroundA malaria vaccine based on Plasmodium falciparum apical membrane antigen 1 (AMA1) elicited strain specific efficacy in Malian children that waned in the second season after vaccination despite sustained AMA1 antibody titers. With the goal of identifying a humoral correlate of vaccine-induced protection, pre- and post-vaccination sera from children vaccinated with the AMA1 vaccine and from a control group that received a rabies vaccine were tested for AMA1-specific immunoglobulin G… CONTINUE READING
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