Immunoglobulin G responses to a panel of Candida albicans antigens as accurate and early markers for the presence of systemic candidiasis.

@article{Clancy2008ImmunoglobulinGR,
  title={Immunoglobulin G responses to a panel of Candida albicans antigens as accurate and early markers for the presence of systemic candidiasis.},
  author={Cornelius J. Clancy and M. Hong Nguyen and Shaoji Cheng and Hong Huang and Guixiang Fan and Reia A Jaber and John R Wingard and Christina Cline},
  journal={Journal of clinical microbiology},
  year={2008},
  volume={46 5},
  pages={1647-54}
}
Despite shortcomings, cultures of blood and sterile sites remain the "gold standard" for diagnosing systemic candidiasis. Alternative diagnostic markers, including antibody detection, have been developed, but none are widely accepted. In this study, we used an enzyme-linked immunosorbent assay to measure serum antibody responses against 15 recombinant Candida albicans antigens among 60 patients with systemic candidiasis due to various Candida spp. and 24 uninfected controls. Mean immunoglobulin… CONTINUE READING

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