Immunoglobulin E. Current status and clinical laboratory applications.


Reaginic antibodies belong to IgE, which represents a distinct immunoglobulin class. Human IgE binds with basophil granulocytes and mast cells through the Fc portion of the molecules and mediates the release of chemical mediators that cause allergic symptoms. The initial step of the reaginic hypersensitivity reaction is probably the bridging of cell-bound… (More)


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@article{Ishizaka1976ImmunoglobulinEC, title={Immunoglobulin E. Current status and clinical laboratory applications.}, author={K.. Ishizaka and T. Ishizaka}, journal={Archives of pathology & laboratory medicine}, year={1976}, volume={100 6}, pages={289-92} }